Key result
In 2019, low physical activity accounted for 8.5% of Type 2 diabetes deaths and 6.9% of Disability-Adjusted Life Years globally, with disability rates projected to increase through 2050.
Why the study?
T2DM poses a major global health burden, but epidemiological research on the impact of low physical activity is limited.
What is the global impact of low physical activity on Type 2 diabetes mellitus mortality and DALYs?
Observational
Yes
What is the global impact of low physical activity on Type 2 diabetes mellitus mortality and DALYs?
Low physical activity is a significant and growing contributor to the global burden of Type 2 diabetes, particularly in low socio-demographic index regions, highlighting the critical need for physical activity promotion.
Answers are grounded in this paper and cite their sources.
LPA-attributable T2DM burden rose 1990-2019, especially in low-SDI regions; leaves open whether activity promotion reduces outcomes in observational data.
BACKGROUND: Type 2 diabetes mellitus (T2DM) poses a major global health burden, yet epidemiological research on low physical activity's (LPA) impact is limited. This study examines LPA's global effect on T2DM. METHODS: Analyzing Global Burden of Disease Database (GBD) 2019, we explored LPA-attributable T2DM deaths and Disability-Adjusted Life Years (DALYs) from 1990 to 2019, stratified by year, gender, country, and SDI regions. Estimated Annual Percentage Change (EAPC) assessed trends, and Bayesian models predicted future patterns. RESULTS: In 2019, LPA accounted for a substantial 8.5% of T2DM deaths and 6.9% of DALYs, representing a noticeable rise since 1990. Age-standardized mortality rates (ASMR) and disability-adjusted life years rates (ASDR) increased globally, particularly in low Socio-Demographic Index (SDI) regions. High and high-middle SDI regions saw a decrease in ASMR, while all regions generally saw an upward trend in ASDR. Projections for 2050 suggest a declining ASMR but an increasing ASDR, indicating a continuing burden of T2DM despite potential mortality reductions. CONCLUSION: LPA significantly impacts T2DM, particularly in low SDI regions. Promotion of physical activity is crucial to reduce this burden, particularly in regions where the disease's impact is most severe.
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Fan et al. (2024) conducted an observational in Type 2 diabetes mellitus. Low physical activity was evaluated on T2DM deaths and Disability-Adjusted Life Years (DALYs). In 2019, low physical activity accounted for 8.5% of Type 2 diabetes deaths and 6.9% of Disability-Adjusted Life Years globally, with disability rates projected to increase through 2050.
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