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Plasma 11-OHCS and Questionary Results (Means + S. D.) This small study suggests that poor short- term response to antidepressants is related to hypothalamic dysfunction.This lack of response and the presence of hypothalamic dysfunction could not have been predicted from clinical or questionary data.Further studies of specific treatment responses and tests of hypothalamic function are needed in depressed patients.If these findings are replicated, they may be of clinical value in deciding on appropriate treatment for the particular patient and may help in eluci- dating the action of antidepressants.-Weare, etc.,
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K. Zinnemann (1970) studied this question.
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