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August 1, 2019HeliyonOpen Access

Neuromuscular effects of dorsiflexor training with and without blood flow restriction

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Key result

Blood flow restriction training resulted in significantly higher muscle activation during the last 20 contractions compared to training without restriction, though post-training neuromuscular effects were similar.

Why the study?

Before blood flow restriction training is used in elderly and clinical populations with weakness, it is important to understand its neurological effects and subject perceptions.

Does blood flow restriction training alter neuromuscular responses compared to training without restriction in healthy subjects?

Comparison

BFRT vs training without blood flow restriction (TR-only)

Design

Crossover study with 2 experimental sessions on separate days

Follow-up

20-min-post exercise

Authors

SKSimon Svanborg KjeldsenAarhus UniversityENErhard Trillingsgaard Næss‐SchmidtAarhus UniversityGHGunhild Mo HansenUniversity College of Northern Denmark

Discussion

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Overview

BFRT does not alter post-exercise cortical excitability versus traditional training; leaves open its role in clinical neuromuscular rehabilitation.

Study Design

Type

RCT (n=17)

Randomization

Randomly allocated to perform TR or BFRT on the first day

Multicenter

No

Structured PICO

Does blood flow restriction training alter neuromuscular responses compared to training without restriction in healthy subjects?

P
Population
17 healthy adults (mean age 35, 53% female) who performed dorsiflexor training with and without blood flow restriction in a randomized crossover design.
I
Intervention
Blood flow restriction training (BFRT) consisting of 4 sets of concentric/eccentric dorsiflexion contractions against theraband resistance
C
Comparator
Training without blood flow restriction (TR-only)
O
Outcome
Neurological effects including motor evoked potentials (MEPs), short-interval intracortical inhibition (SICI), intracortical facilitation (ICF), and M-max amplitudesurrogate

Main Result

p-value: p=0.009

Blood flow restriction training induces similar post-training neuromuscular fatigue as conventional training but increases muscle activation during exercise, albeit with greater perceived discomfort.

Limitations

  • Blood pressure was taken at the arm and used as the occlusion pressure for the leg.
  • The study was powered based on a different protocol, so non-significant interaction effects might be due to an underpowered experimental design.
  • Mechanisms can only be inferred from surface EMG amplitude, which is a net effect of multiple physiological changes.

Cite This Study

Kjeldsen et al. (2019) conducted an RCT in Healthy (n=17). Blood flow restriction training (BFRT) vs. Training without blood flow restriction (TR-only) was evaluated on Surface EMG amplitude during training (muscle activation) (p=0.009). Blood flow restriction training resulted in significantly higher muscle activation during the last 20 contractions compared to training without restriction, though post-training neuromuscular effects were similar.

synapsesocial.com/papers/6a9d5a2ebbd60fd57f67eec1https://doi.org/10.1016/j.heliyon.2019.e02341
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Muscular adaptations to fatiguing exercise with and without blood flow restriction2014 · 162 citations
  2. 2Unilateral bicep curl hemodynamics: Low‐pressure continuous vs high‐pressure intermittent blood flow restriction2014 · 103 citations
  3. 3Effects of resistance exercise combined with moderate vascular occlusion on muscular function in humans2000 · 857 citations
  4. 4Corticocortical inhibition in human motor cortex.1993 · 3,166 citations
  5. 5Corticomotor Excitability is Increased Following an Acute Bout of Blood Flow Restriction Resistance Exercise2015 · 77 citations