Key result
Transfer from hemodialysis to peritoneal dialysis after at least 3 months of HD therapy was associated with significantly reduced overall survival compared to initial peritoneal dialysis.
Why the study?
Outcomes of patients transferred to peritoneal dialysis after an initial phase of hemodialysis compared to patients initiating dialysis with peritoneal dialysis remain controversial.
Does transfer from hemodialysis to peritoneal dialysis improve overall survival in patients requiring dialysis?
Population
Patients transferred to PD after HD vs patients initiating dialysis with PD
Comparison
Transfer from HD to PD vs PD as initial therapy
Design
Systematic review and meta-analysis
Authors
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Supports PD-first policy to avoid reduced survival with late transfer; reinforces meta-analytic evidence favoring initial peritoneal dialysis.
Meta-Analysis
Does transfer from hemodialysis to peritoneal dialysis improve overall survival in patients requiring dialysis?
Patients transferred from hemodialysis to peritoneal dialysis have reduced overall survival and higher technique failure compared to those initiating dialysis with peritoneal dialysis, supporting a PD-first policy.
Wang et al. (2020) conducted a meta-analysis in Patients requiring dialysis. Transfer from hemodialysis to peritoneal dialysis vs. Peritoneal dialysis as initial therapy was evaluated on Overall survival (OS). Transfer from hemodialysis to peritoneal dialysis after at least 3 months of HD therapy was associated with significantly reduced overall survival compared to initial peritoneal dialysis.
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