Key result
Practical diagnostic virology relies on optimal viral isolation, pathological examination, and supplementary serological studies to provide useful clinical information.
Provides a brief overview of practical diagnostic virology methods including viral isolation, pathological examination, and serological studies.
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Supports multimodal viral diagnostics in pediatrics; leaves open prospective validation of clinical impact.
The clinician has several means for obtaining useful viral diagnostic information. Those for viral isolation require optimal conditions; specimens must be submitted quickly in an appropriate medium, with the information that is essential to the laboratory. Viral diagnosis may also be facilitated by pathological examination of tissues, body fluids, vesicles, and so forth. Viral culture information should be supplemented by appropriate serological studies done on acute and convalescent serum specimens. A brief discussion of the types of antibody measurement commonly used has been included.
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Catherine M. Wilfert (1968) conducted a review in Viral infection. Practical diagnostic virology relies on optimal viral isolation, pathological examination, and supplementary serological studies to provide useful clinical information.
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