Key result
Diuretics lead antihypertensive prescriptions, while propranolol is overutilized at ~1.7 times the defined daily dose.
Why the study?
Evaluating antihypertensive use with the defined daily dose method helps track prescription drug usage and examine drug usage trends.
Observational (n=285)
No
This drug utilization study highlights the prescribing patterns of antihypertensives in an Indian hospital, revealing potential overuse of beta-blockers like propranolol.
Answers are grounded in this paper and cite their sources.
May signal guideline-practice gaps in antihypertensive use; leaves open whether stewardship improves outcomes in similar cohorts.
The DDD concept is a method for quantifying a drug. Drug use in terms of DDD aids in converting the number of pharmaceuticals readily available into medically significant units and in estimating the number of people who have been exposed to a specific drug or class of drugs. In a hospital setting, the unit DDD per 100 bed-days suggests the proportion of inpatients that may receive a DDD. DDD in anti-hypertensive medications helps to track down prescription drug usage and examine drug usage trends. A 6-month prospective and observational study was conducted to assess the drug utilisation of antihypertensives. In this study we found that Diuretics were commonly prescribed antihypertensives. Furosemide and Spironolactone were mostly prescribed antihypertensives as single therapy, while Telmisartan+Hydrochlorothiazide was commonly prescribed as combination therapy. Propranolol was over utilised antihypertensives with 187.82 DDD/100bed-days and 1.74 PDD:DDD ratio.
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- et al. (2023) conducted an observational in Hypertension (n=285). Antihypertensive medications was evaluated on Drug utilization measured by Defined Daily Dose (DDD) per 100 bed-days and Prescribed Daily Dose to DDD ratio (PDD:DDD). Diuretics were the most commonly prescribed antihypertensives, while Propranolol was found to be overutilized with 187.82 DDD/100 bed-days and a PDD:DDD ratio of 1.74.
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