Key result
Newborn lambs demonstrated vigorous myocardial performance equaling or exceeding adult ewes, with left ventricular dP/dtmax averaging 3,723 mmHg/s in lambs compared to 2,257 mmHg/s in ewes.
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Challenges assumptions of immature neonatal myocardium; leaves open translation to human infants and clinical relevance.
Berman et al. (1979) studied this question. Newborn age (first 3 weeks of life) vs. Adult ewes was evaluated on Myocardial performance (including cardiac output, stroke work, and left ventricular dP/dtmax). Newborn lambs demonstrated vigorous myocardial performance equaling or exceeding adult ewes, with left ventricular dP/dtmax averaging 3,723 mmHg/s in lambs compared to 2,257 mmHg/s in ewes.
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