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January 1, 2012HOAJ BiologyOpen Access

Chlorogenic acid from the Japanese herbal medicine Kinginka (Flos Lonicerae japonicae) suppresses the expression of inducible nitric oxide synthase in rat hepatocytes

Naomi Ohno Emi Yoshigai Tetsuya Okuyama Yuka Yamamoto Tadayoshi Okumura Kenji Sato Yukinobu Ikeya Mikio Nishizawa

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Abstract

Background: Flos Lonicerae japonicae (FLJ; Kinginka) is the dried flowers and buds of the Japanese honeysuckle Lonicera japonica Thunberg. FLJ has been used as a Japanese Kampo medicine to treat

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Ohno et al. (2012) studied this question.

synapsesocial.com/papers/6a9d69d3843eea9644fceb34 https://doi.org/10.7243/2050-0874-1-2

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Simultaneous determination of iridoids, phenolic acids, flavonoids, and saponins in Flos Lonicerae and Flos Lonicerae Japonicae by HPLC‐DAD‐ELSD coupled with principal component analysisOriginal Research · 2007 · 71 citations
2Anti-Inflammatory and Analgesic Activities of SKLJI, a Highly Purified and Injectable Herbal Extract of Lonicera japonicaOriginal Research · 2010 · 51 citations
3Japanese herbal medicine, inchinkoto, inhibits inducible nitric oxide synthase induction in interleukin‐1β‐stimulated hepatocytesOriginal Research · 2011 · 19 citations
4Interleukin 1 beta markedly stimulates nitric oxide formation in the absence of other cytokines or lipopolysaccharide in primary cultured rat hepatocytes but not in Kupffer cellsOriginal Research · 1996 · 113 citations
5Synergistic regulation of inducible nitric oxide synthase gene by CCAAT/enhancer‐binding protein β and nuclear factor‐κB in hepatocytesOriginal Research · 1998 · 62 citations

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