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NH&erminalsequences were determined for human plasminogen and the S-carboxymethyl heavy (A) and light (B) chain derivatives of plasmin with a protein sequenator.The NH2-terminal 5 residues of plasminogen and the isolated S-carboxymethyl heavy (A) chain derivative isolated from plasma Fraction II12,s were determined to be Lys-Val-Tyr-Leu-Leu-.A second identical repeating des-lysyl sequence was found.
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Robbins et al. (1972) studied this question.
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