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In a murine model for allogeneic bone marrow transplantation, we used chimerism analysis to demonstrate that durable engraftment of donor-type hematopoietic cells following conditioning with 8Gy Total Body Irradiation was enhanced by additional treatment of the host with a myeloablative drug, Thiotepa or Busulphan and to compare to the activity of cyclophosphamide
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A 1990 study studied this question.
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