Unexpectedly High Activity of Zn(OTf)2 · 6H2O in Catalytic Friedel–Crafts Acylation Reaction

Zn(OTf)2 · 6H2O was used to promote Friedel–Crafts acylation of aromatics. The work describes the high activity and efficiency of Zn(OTf)2 · 6H2O in acylation of aromatics, and the catalyst has surpassed most metal triflates in dispensing when dried at high temperature under vacuum before use.