Surprising outcome similarities between Contegra® bovine jugular vein conduit and Shelhigh No-React® porcine pulmonary valve conduit: role of immunologic reaction
Key result
Contegra and Shelhigh conduits share similar failure mechanisms, including extensive intimal proliferation and potential aneurysmal dilatation, likely driven by host immunologic reactions.
Design
Editorial
Authors
Discussion
Loading...
Member takes
Implication
Failure of Contegra and Shelhigh conduits share similar complications such as distal obstruction and aneurysmal dilatation, suggesting a potential role of host immunologic reaction.
PICO
P
Population
Conduit failure in pulmonary valve replacement
E
Exposure / Comparator
Contegra bovine jugular vein conduit and Shelhigh No-React porcine pulmonary valve conduit vs Classical synthetic conduits (historical)
Failure of Contegra and Shelhigh conduits share similar complications such as distal obstruction and aneurysmal dilatation, suggesting a potential role of host immunologic reaction.
Cite This Study
Boudjemline et al. (2003) conducted a letter in Conduit failure in pulmonary valve replacement. Contegra bovine jugular vein conduit and Shelhigh No-React porcine pulmonary valve conduit vs. Classical synthetic conduits (historical) was evaluated. Contegra and Shelhigh conduits share similar failure mechanisms, including extensive intimal proliferation and potential aneurysmal dilatation, likely driven by host immunologic reactions.