Key result
The overall prevalence of antihypertensive medication non-adherence was 65.8%, with self-efficacy and social support identified as significant predictors of adherence.
Why the study?
The prevalence of and factors associated with antihypertensive medication non-adherence among hypertension care seekers attending primary health clinics in the Gaza Strip were not established.
Cross-Sectional (n=538)
Two-stage cluster random sampling
Yes
A high prevalence of antihypertensive medication non-adherence (65.8%) was found among patients in the Gaza Strip, strongly associated with poor self-efficacy and lack of social support.
BACKGROUND: This study aimed to estimate the prevalence of and determine the factors associated with antihypertensive medication (A-HTNM) non-adherence among hypertension care seekers attending primary health clinics in the Gaza Strip. METHODS: A cross-sectional survey was conducted as the recruitment phase of a clustered randomized controlled trial including 538 participants. The participants were randomly selected from 10 primary health care centers by two-stage cluster random sampling. A structured questionnaire was used to collect data through face-to-face interview. The questionnaire was developed based on the World Health Organization determinants for medication non-adherence and the Health Belief Model. The main outcomes of this study were the prevalences of A-HTNM non-adherence and its associated factors. Adherence status was assessed using the eight-item Morisky Self-Report Medication Adherence Scale. Data were analyzed by STATA ver. 14.0 (Stata Corp., College Station, TX, USA) using a standard complex survey, accounting for unresponsiveness and the clustering sampling approach. RESULTS: The overall prevalence of A-HTNM non-adherence was 65.8% (95% confidence interval [CI], 59.2-71.8). Among all studied predictors, only self-efficacy of participants (odds ratio [OR], 3.8; 95% CI, 1.79-2.84) and social support (OR, 2.26; 95% CI, 2.82-5.11) remained significantly associated with A-HTNM non-adherence after adjusting for age, education level, number and frequency of A-HTNM doses per day, and comorbidities. CONCLUSION: The high prevalence of non-adherence highlights the need for serious intervention to enhance the adherence rate among hypertension patients. The associated factors can be considered when developing appropriate interventions.
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Khadoura et al. (2020) conducted a cross-sectional in Hypertension (n=538). Predictors of medication non-adherence (e.g., self-efficacy, social support) was evaluated on Prevalence of antihypertensive medication non-adherence (95% CI 59.2-71.8). The overall prevalence of antihypertensive medication non-adherence was 65.8%, with self-efficacy and social support identified as significant predictors of adherence.
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