Key result
Marek's disease virus continues to evolve towards higher virulence, necessitating the continuous development and updating of vaccines, including gene-deleted and recombinant vector vaccines.
Why the study?
Control of Marek's disease mainly relies on vaccine immunization, which is challenged by the continuous evolution of the virus towards stronger virulence requiring vaccines to be constantly updated.
The continuous evolution of Marek's disease virus towards higher virulence necessitates the constant updating and development of novel genetically engineered vaccines for poultry farming.
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May support updated poultry vaccines; leaves open prospective validation of recombinant candidates.
Changjun Liu (2023) conducted a review in Marek's disease. Marek's disease vaccines was evaluated. Marek's disease virus continues to evolve towards higher virulence, necessitating the continuous development and updating of vaccines, including gene-deleted and recombinant vector vaccines.
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