Coronary risk factors in angiographically defined patients with chest pain.

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Chest pain (n=186). Intervention: High serum cholesterol (>240 mg/dl) vs. Desirable serum cholesterol (<199 mg/dl). Primary outcome: Coronary sclerosis index (CSI) in subjects under 55 years of age (p=0.0072).

Takao Fujinami; Hiroyuki Hirata; Junichiro Hayano; Nobuyuki Ohte; M Kohketsu; Takeshi Hashimoto

doi:10.2169/internalmedicine1962.29.462

January 1, 1990Japanese Journal of MedicineOpen Access

Coronary risk factors in angiographically defined patients with chest pain.

View Full Paper

Ask AI

Bookmark

Share

Study Design

Type

Cross-Sectional (n=186)

Multicenter

No

Structured PICO

P

Population

186 consecutive patients (34.4% female, mean age 55.7 years) with chest pain undergoing coronary angiography to evaluate coronary risk factors.

O

Outcome

Severity of coronary luminal narrowing scored as the coronary sclerosis index (CSI)surrogate

Main Result

Absolute Event Rate: 7.36% vs 2.05%

p-value: p=0.0072

Limitations

A computerized image analyzer was not available for this study.
The angiogram is a luminogram and the width of original arterial lumen is unknown, so the least narrowed segment is often presumed to be normal.
Subjects with myocardial infarction were excluded from the analysis of type A behavior to avoid lifestyle modification bias.
A computerized image analyzer was not available for this study
The angiogram is a luminogram and the width of original arterial lumen is unknown, so the least narrowed segment is often presumed to be normal

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Disorders in lipid metabolism, such as elevated LDL or diminished HDL cholesterol, are pertinent risk factors for the progression of coronary sclerosis in early middle age and should be corrected.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Fujinami et al. (1990) conducted a cross-sectional in Chest pain (n=186). High serum cholesterol (>240 mg/dl) vs. Desirable serum cholesterol (<199 mg/dl) was evaluated on Coronary sclerosis index (CSI) in subjects under 55 years of age (p=0.0072).

synapsesocial.com/papers/6a9d8571d8a02169be46eced https://doi.org/10.2169/internalmedicine1962.29.462

View Full Paper

Ask AI

Bookmark

Share

Coronary risk factors in angiographically defined patients with chest pain.

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Coronary risk factors in angiographically defined patients with chest pain.

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading