Key result
Discontinuation of sulpiride and maprotiline was associated with the development of neuroleptic malignant syndrome and acute myoglobinuric renal failure in a 46-year-old man.
Population
46-year-old man
Design
Case_report
Authors
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May indicate NMS risk after sulpiride/maprotilline withdrawal; first case leaves causality and incidence open.
Case Report (n=1)
No
This is the first reported case of neuroleptic malignant syndrome and acute myoglobinuric renal failure following the discontinuation of sulpiride and maprotiline.
Kiyatake et al. (1991) conducted a case report in Neuroleptic malignant syndrome with acute renal failure (n=1). Discontinuation of sulpiride and maprotiline was evaluated on Development of neuroleptic malignant syndrome and acute myoglobinuric renal failure. Discontinuation of sulpiride and maprotiline was associated with the development of neuroleptic malignant syndrome and acute myoglobinuric renal failure in a 46-year-old man.
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