Key result
Contemporary DES undergo longitudinal length change in ~83% of IVUS-guided deployments, predominantly elongating.
Why the study?
Contemporary thin-strut drug-eluting stents frequently alter longitudinal length after deployment, but contemporary IVUS-guided in-vivo data from South-Asian populations remain limited.
Observational (n=80)
No
Longitudinal stent length change is common after IVUS-guided PCI with contemporary DES, predominantly elongation, which is associated with higher post-dilation pressures and smaller reference vessel sizes.
Answers are grounded in this paper and cite their sources.
May warrant adjusted stent selection accounting for post-deployment changes; Level 5 data leaves open clinical consequences and need for prospective validation.
OBJECTIVE: Contemporary thin-strut drug-eluting stents (DES) frequently undergo a change in longitudinal length after deployment. Contemporary intravascular ultrasound (IVUS)-guided in-vivo data from South-Asian populations remain limited. METHODS: We prospectively studied 80 consecutive de-novo coronary lesions treated by IVUS-guided percutaneous coronary intervention. Stent length was measured by edge-to-edge (E-E) and area-to-area (A-A) IVUS techniques, compared with the manufacturer box-stated length, and classified as elongated, shortened or unchanged. RESULTS: Mean age was 58.3 ± 11.8 years (88.8% male). Stent length change occurred in 66 of 80 stents (82.5%) - elongation in 44 (55.0%), shortening in 22 (27.5%), unchanged in 14 (17.5%), with mean length differences of +1.23, -1.00, and +0.02 mm. Elongation exceeded 1 mm in 24 stents (30.0%) and 2 mm in 6 (7.5%); shortening exceeded 1 mm in 10 (12.5%). Reference lumen diameter (p = 0.030) and area (p = 0.011) differed across groups. On multivariable regression, both post-dilation pressure (p = 0.004) and reference lumen diameter (p = 0.026) remained independently associated with length change. All six stents with elongation >2 mm occurred at post-dilation pressures ≥20 atm; half were in left main-left anterior descending (LM-LAD) stents, and the three longest elongations were all in LM-LAD stents. Shortening was more than twice as common in LM-LAD than non-LM-LAD stents (45.0% vs 21.7%; Fisher p = 0.080). CONCLUSIONS: Longitudinal stent length change is common on post-PCI IVUS assessment, with elongation predominating. LM-LAD stents showed a bimodal pattern, with both the largest elongations and disproportionate shortenings clustering at this location. Higher post-dilation pressure and smaller reference vessel size were associated with greater elongation.
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Yousuf et al. (2026) conducted an observational in de-novo coronary lesions (n=80). IVUS-guided percutaneous coronary intervention with contemporary drug-eluting stents vs. Manufacturer box-stated length was evaluated on Longitudinal stent length change (elongated, shortened or unchanged). Longitudinal stent length change occurred in 82.5% of contemporary drug-eluting stents after IVUS-guided deployment, with elongation predominating (55.0%).
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