Key result
ECHO-13 virus was isolated from 10 apparently healthy children in the Philippines, with neutralizing and complement-fixing antibody rises demonstrated in an infected infant and family members.
Population
10 apparently healthy children in the Philippine Islands and 11 other individuals with serologic evidence of…
Design
Cohort
Authors
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Documents asymptomatic ECHO-13 circulation in children; leaves open its potential role in CNS disease.
Observational (n=12)
No
ECHO-13 virus can infect healthy individuals and elicit transient antibody responses, with presumptive but inconclusive evidence of a potential to cause central nervous system disease.
Hammon et al. (1961) conducted an observational in ECHO virus type 13 infection (n=12). ECHO virus type 13 infection was evaluated on Virus isolation and serologic response (neutralizing and complement-fixing antibodies). ECHO-13 virus was isolated from 10 apparently healthy children in the Philippines, with neutralizing and complement-fixing antibody rises demonstrated in an infected infant and family members.
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