Key result
Female sex is an independent predictor of 30-day mortality after isolated coronary artery bypass grafting, with women experiencing a significantly higher mortality rate than men (7.6% vs 2.8%, OR 1.81).
Why the study?
Does female sex independently predict higher 30-day mortality in patients undergoing isolated coronary artery bypass grafting?
Cohort (n=1,197)
No
Does female sex independently predict higher 30-day mortality in patients undergoing isolated coronary artery bypass grafting?
Odds Ratio: 1.81 (95% CI 1.21–2.69)
Absolute Event Rate: 7.6% vs 2.8%
p-value: p=<0.001
Female sex is an independent predictor of higher 30-day mortality after isolated CABG, highlighting the need to understand and mitigate gender-specific risks in surgical revascularization.
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May warrant enhanced perioperative monitoring in women undergoing CABG; extends observational data but remains hypothesis-generating.
Miśkowiec et al. (2015) conducted a cohort in Coronary artery disease requiring isolated coronary artery bypass grafting (CABG) (n=1,197). Female sex vs. Male sex was evaluated on 30-day mortality (OR 1.81, 95% CI 1.21-2.69, p=<0.001). Female sex is an independent predictor of 30-day mortality after isolated coronary artery bypass grafting, with women experiencing a significantly higher mortality rate than men (7.6% vs 2.8%, OR 1.81).
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