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The same author has recently presented and discussed the problems of diagnosis and briefly touched on the prophylaxis of bacterial endocarditis in a recent issue.2 The present discussion will, therefore, be limited chiefly to a consideration of certain topics of current interest. These will include: (1) the optimum method of admin- istration of penicillin, (2) the use of antibiotics other than penicillin, and (3) the treatment of patients with negative blood cultures.
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Maxwell Finland (1954) studied this question.
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