Key result
Implantation of a human homograft aortic valve preserved in buffered formaldehyde for six months was reported for the first time.
Case Report
This early communication reports the first use of formaldehyde in acetate buffer for the preservation of human homograft aortic valves for transplantation.
Buffered formaldehyde may enable longer homograft valve storage; leaves open durability, safety, and need for prospective validation.
by the insertion of a homograft aortic valve. The valve had been stored in buffered formaldehyde for six months, and this technique of preservation is the purpose of this communication. Formaldehyde in acetate buffer for the preserva-tion of valve tissue was suggested to us by Lord Brock (1962), and this report of its use is believed to be the first. The successful implantation of homograft aortic valves in the subcoronary position was first reported by Ross (1962, 1963). In his series, homo-graft valves were removed under clean but non-sterile conditions within 12 hours of death, placed in a dilute chlorhexidine solution ('Hibitane'), and kept at approximately 4 ° C. until they were finally
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Paneth et al. (1966) reported a case report. Homograft aortic valve stored in buffered formaldehyde was evaluated. Implantation of a human homograft aortic valve preserved in buffered formaldehyde for six months was reported for the first time.
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