Key result
Isolated systolic hypertension in elderly men was associated with higher plasma viscosity compared to normotensive controls (1.39 vs 1.34 cP, P<0.01), with pulse pressure as a major determinant.
Why the study?
Is plasma viscosity increased in elderly men with isolated systolic hypertension, and does it correlate with pulse pressure?
Observational (n=168)
Is plasma viscosity increased in elderly men with isolated systolic hypertension, and does it correlate with pulse pressure?
Absolute Event Rate: 1.39% vs 1.34%
p-value: p=<.01
Plasma viscosity is elevated in elderly men with isolated systolic hypertension and is independently associated with pulse pressure, suggesting a link between pulsatile hemodynamics and systemic inflammation.
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Should not change ISH management; leaves open whether pulse pressure drives plasma viscosity in elderly men.
Ciuffetti et al. (2005) conducted an observational in Isolated systolic hypertension (n=168). Isolated systolic hypertension vs. Normotensive controls was evaluated on Plasma viscosity (p=<.01). Isolated systolic hypertension in elderly men was associated with higher plasma viscosity compared to normotensive controls (1.39 vs 1.34 cP, P<0.01), with pulse pressure as a major determinant.
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