What question did this study set out to answer?

Determine whether native bovine serum albumin can be recovered following precipitation with trichloroacetic acid and subsequent dissolution in organic solvents.

January 1, 1957Journal of the American Chemical Society

Recovery of Native Bovine Serum Albumin after Precipitation with Trichloroacetic Acid and Solution in Organic Solvents1

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Authors

GSGeorge W. SchwertUniversity of Kentucky

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Implication

Laboratory study demonstrates recovery of native bovine serum albumin after trichloroacetic acid precipitation, suggesting protein denaturation by strong acids can be reversed.

Key Points

Determine whether native bovine serum albumin can be recovered following precipitation with trichloroacetic acid and subsequent dissolution in organic solvents.
Precipitated bovine serum albumin using trichloroacetic acid.
Dissolved the resulting precipitate in organic solvent systems to evaluate protein renaturation.
Bovine serum albumin successfully regained its native state after precipitation with trichloroacetic acid.
Organic solvent treatment effectively facilitated the solubilization and recovery of the precipitated protein.

Cite This Study

George W. Schwert (1957) studied this question.

synapsesocial.com/papers/6a9db16e34685bd7702a1648 https://doi.org/10.1021/ja01558a035

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Implication

Laboratory study demonstrates recovery of native bovine serum albumin after trichloroacetic acid precipitation, suggesting protein denaturation by strong acids can be reversed.

Recovery of Native Bovine Serum Albumin after Precipitation with Trichloroacetic Acid and Solution in Organic Solvents1

Discussion

Member takes

Implication

Key Points

Cite This Study

Recovery of Native Bovine Serum Albumin after Precipitation with Trichloroacetic Acid and Solution in Organic Solvents1

Discussion

Member takes

Implication

Key Points

Cite This Study

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