Ampicillin and urticaria.

MEDIISOURshowed crystal clear fluid under normal pressure.Microscopic examination showed no cells, and the protein content was 35 mg./100 ml.It was thought that the hypertensive crisis might be a consequence of the drug therapy.In case the administration of pethidine was a contributory factor, she was treated with a forced acid diuresis and a minimal urine pH of 4-8 was obtained.The blood pressure started to fall and by 10 hours after the ingestion of Mucron it had reached a level of 130/70.The blood pressure remained normal during the rest of her stay in hospital, and on follow-up one month later she was normotensive and asympto- matic apart from a mild depression.a limited number of patients with this type of rash investigated so far we have been unable to demonstrate circulating reaginic antibodies in the serum.It is now well established that