Endocardial Fibroelastosis With Generalized Lymphadenopathy, Oedema, and Rash

Endocardial fibroelastosis of the heart has attracted much attention in recent years and pub- lished case reports have been fully reviewed by A further review would seem unjustified, but we wish to report two cases of endocardial fibroelastosis associated with unusual clinical and pathological features. CASE REPORTS Case 1. This boy was perfectly well until the age of eight and a half months when he developed a running nose with intermittent pyrexia and cough and his cervical lymph nodes were noticed to be enlarged. At the age of ten months his mother observed that he had a swelling in the left groin and that his feet and face were swollen. His urine was found to contain albumin. He was admitted to the Montagu Hospital, Mexborough, under the care of Dr. C. C. Harvey and at eleven months was transferred to the Sheffield Children's Hospital. On admission he was a pale, ill-looking child weighing 10-6 kg. with pitting cedema over his legs and back. He had a generalized enlargement of his lymph nodes, one in the left groin being especially prominent. His liver and spleen were both easily palpable but no other abnormal physical signs were detected. His heart at that time was thought to be normal. His blood pressure was 95/55.