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February 1, 1951PEDIATRICS

Endocardial Fibroelastosis

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Key result

Microscopic evaluation of two new cases of endocardial fibroelastosis demonstrated hyperplasia of fibrous and elastic tissue elements, consistent with 11 previously reviewed cases.

Population

13 cases of fibroelastosis of the endocardium (11 reviewed, 2 new cases reported)

Design

Case_series

Authors

FCFred C. CollierCleveland State UniversityPRPaul D. RosahnRockefeller Foundation

Discussion

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Implication

Supports fetal developmental pathogenesis in EFE; hypothesis-generating and requires validation beyond case reports.

Study Design

Type

Case Report (n=13)

Structured PICO

P
Population
13 cases (11 reviewed and 2 new) of endocardial fibroelastosis.
O
Outcome
Microscopic evidence of hyperplasia of the fibrous and elastic tissue elements of the endocardium

The study reports microscopic evidence of hyperplasia in endocardial fibroelastosis, suggesting a fetal developmental aberration as its pathogenesis.

Limitations

  • The pathogenesis of the lesion is at present not clear

Cite This Study

Collier et al. (1951) conducted a case report in Endocardial fibroelastosis (n=13). Microscopic evaluation of two new cases of endocardial fibroelastosis demonstrated hyperplasia of fibrous and elastic tissue elements, consistent with 11 previously reviewed cases.

synapsesocial.com/papers/6a975f9edfe10a478e9d92ffhttps://doi.org/10.1542/peds.7.2.175
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Endocardial Fibroelastosis: A Comprehensive Review2024 · 1 citations
  2. 2Endocardial Fibroelastosis1964 · 93 citations
  3. 3ENDOCARDIAL FIBRO-ELASTOSIS1956 · 86 citations
  4. 4Endocardial Fibroelastosis: Roentgen Appearance1955 · 11 citations
  5. 5Endocardial Fibroelastosis1958 · 20 citations