Key result
Among elderly men with prostate cancer, depression during the treatment phase was associated with an increased risk of death (HR 2.82; 95% CI 2.60-3.06) and higher healthcare utilization.
Why the study?
Does depression increase health resource utilization, costs, and mortality in elderly patients with prostate cancer?
Population
50,147 elderly patients newly diagnosed with prostate cancer between 1995 and 1998
Comparison
Diagnosis of depression during treatment phase… vs Men with prostate cancer without a diagnosis of…
Design
Cohort
Follow-up
up to 8 years post diagnosis
Authors
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May identify high-risk elderly prostate cancer patients; hypothesis-generating for whether depression treatment improves survival or lowers utilization.
Cohort (n=50,147)
Yes
Does depression increase health resource utilization, costs, and mortality in elderly patients with prostate cancer?
Hazard Ratio: 2.82 (95% CI 2.6–3.06)
Depression in elderly men with prostate cancer is associated with significantly increased healthcare utilization, costs, and mortality.
Jayadevappa et al. (2011) conducted a cohort in Prostate cancer (n=50,147). Depression vs. No depression was evaluated on Mortality (HR 2.82, 95% CI 2.60-3.06). Among elderly men with prostate cancer, depression during the treatment phase was associated with an increased risk of death (HR 2.82; 95% CI 2.60-3.06) and higher healthcare utilization.
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