Key result
Hemoperfusion successfully reduced plasma digoxin levels from >6.00 ng/mL to 4.6 ng/mL and resolved clinical symptoms in a 61-year-old chronic hemodialysis patient with digitalis intoxication.
Why the study?
Does hemoperfusion reduce digoxin levels in a chronic hemodialysis patient with digitalis intoxication?
Case Report (n=1)
No
Does hemoperfusion reduce digoxin levels in a chronic hemodialysis patient with digitalis intoxication?
Hemoperfusion may be an effective treatment for reducing digoxin levels and resolving toxicity symptoms in chronic hemodialysis patients with digitalis intoxication.
May support hemoperfusion for digoxin toxicity in hemodialysis; hypothesis-generating and requires controlled trials.
Diagnosis of Digitalis intoxication depends on good history taking, clinical signs and symptoms, and digoxin level. Sixty one years old female with diabetes mellitus (DM), coronary artery disease (CAD) and end-stage renal failure administered to emergency department with complaints of dyspnea and chest pain. Digoxin 0.50 mg once a day was prescribed by an internal medicine physician and she has been taking the drug for 7 days. In our case digoxin level was decreased to valuable level after hemoperfusion. In conclusion it was observed that hemoperfusion therapy of digitalis intoxication in chronic hemodialysis patient is effective.
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Atalay et al. (2008) conducted a case report in Digitalis intoxication in end-stage renal failure (n=1). Hemoperfusion was evaluated on Plasma digoxin level. Hemoperfusion successfully reduced plasma digoxin levels from >6.00 ng/mL to 4.6 ng/mL and resolved clinical symptoms in a 61-year-old chronic hemodialysis patient with digitalis intoxication.
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