Recent Advances in Copper(II)-Mediated or -Catalyzed C–H Functionalization

This review summarizes recent developments in the field of copper-mediated or -catalyzed C–H functionalization. The substrate scope has been expanded from the C–H activation of aryls to more challenging alkyls. Furthermore, catalytic amounts of copper salt are sufficient to promote the challenging C–H functionalization in some cases, which represents the focus of future research. 1 Introduction 2 C–C Bond Formation 3 C–N Bond Formation 4 C–O Bond Formation 5 C–Halogen Bond Formation 6 C–S Bond Formation 7 Conclusions and Outlook