Key result
A simplified artificial material model yielded >20% relative differences in peak wall stress and rupture risk in 10% of abdominal aortic aneurysms compared to a realistic reference model.
Why the study?
Does a simplified artificial material model accurately predict peak wall stress and rupture risk in abdominal aortic aneurysms compared to a realistic material model?
Does a simplified artificial material model accurately predict peak wall stress and rupture risk in abdominal aortic aneurysms compared to a realistic material model?
Realistic material models are favored for clinical practice in AAA rupture risk prediction, as simplified models yield >20% error in about 10% of cases.
Simplified models may misclassify AAA rupture risk in 10% of cases; leaves open whether realistic modeling improves risk stratification.
In the paper impact of different material models on the calculated peak wall stress (PWS) and peak wall rupture risk (PWRR) in abdominal aortic aneurysms (AAAs) is assessed. Computational finite element models of 70 patient-specific AAAs were created using two different material models - a realistic one based on mean population results of uniaxial tests of AAA wall considered as reference, and a 100 times stiffer artificial model. The calculated results of PWS and PWRR were tested to evaluate statistical significance of differences caused by the non-realistic material model. It was shown that for majority of AAAs the differences are insignificant but for some 10% of them their relative differences exceed 20% which may lead to incorrect decisions on their surgical treatment. This percentage of failures favours application of realistic material models in clinical practise although they are much more time-consuming.
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Novák et al. (2017) studied Abdominal aortic aneurysms (n=70). Simplified artificial material model (100 times stiffer) vs. Realistic material model was evaluated on Peak wall stress (PWS) and peak wall rupture risk (PWRR). A simplified artificial material model yielded >20% relative differences in peak wall stress and rupture risk in 10% of abdominal aortic aneurysms compared to a realistic reference model.
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