Key result
In Chinese patients with acute myocardial infarction, percutaneous coronary intervention (PCI) was significantly associated with improved in-hospital prognosis, reducing mortality from 14.1% to 3.06%.
Observational (n=627)
No
In Chinese patients with AMI, older age, lack of PCI, and anterior infarct location are significantly associated with higher in-hospital mortality, while PCI and longer stays drive hospitalization costs.
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PCI associated with lower AMI mortality in Chinese patients; leaves open causal confirmation and generalizability pending RCTs.
Acute myocardial infarction (AMI) is the leading cause of morbidity and mortality in the developed world and is becoming increasingly more common in developing countries. The risk factors affecting the prognosis of Chinese patients may differ from those in other populations. This study was conducted to investigate the potential risk factors that may correlate with prognosis and hospitalization costs of Chinese AMI patients. A total of 627 hospitalized AMI patients were recruited and their general information and relevant laboratory parameters were collected. Accordingly, the patients were grouped into different subgroups and potential risk factors and their correlations with prognosis and hospitalization costs were analyzed. Age, high blood pressure, infarct location and percutaneous coronary intervention (PCI) were the variables significantly associated with the differences in the prognosis of AMI patients (P<0.05), whereas times and duration of hospitalization, high blood pressure, infarct location and PCI treatment were found to be significantly associated with the cost of hospitalization (P<0.05). However, the AMI patients enrolled in this study may not be representative of all AMI patients in China. In addition, the prognosis of these patients was limited to their hospital stay. Therefore, long-term follow-up requires careful assessment.
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Wang et al. (2014) conducted an observational in Acute myocardial infarction (AMI) (n=627). Percutaneous coronary intervention (PCI) vs. No PCI was evaluated on In-hospital mortality (p=<0.0001). In Chinese patients with acute myocardial infarction, percutaneous coronary intervention (PCI) was significantly associated with improved in-hospital prognosis, reducing mortality from 14.1% to 3.06%.
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