Osler-Weber-Rendu Disease: A Rare Contributor to Recurrent Iron Deficiency Anemia

Hereditary hemorrhagic telangiectasia (HHT), also called Osler-Weber-Rendu syndrome, is a rare genetic disorder inherited in an autosomal dominant pattern. It is marked by recurrent nosebleeds, arteriovenous malformations (AVMs), mucocutaneous telangiectasias, and often a family history of the condition. This case involves a 55-year-old woman with a prolonged history of spontaneous bleeding, particularly from lesions on her tongue, leading to chronic iron deficiency anemia. The case emphasizes the importance of considering HHT in patients with anemia and unexplained recurrent bleeding. It also underscores the value of targeted therapies and genetic counseling in managing the disorder.