Key result
Local anesthesia significantly reduced perioperative mortality compared to general anesthesia during endovascular repair of ruptured abdominal aortic aneurysms (OR 0.49; 95% CI 0.35-0.67; p<0.00001).
Why the study?
In the endovascular treatment of ruptured abdominal aortic aneurysm, effective evidence showing a preference for a specific anesthetic option was lacking.
Does local anesthesia reduce perioperative mortality compared to general anesthesia in patients undergoing EVAR for ruptured abdominal aortic aneurysm?
Comparison
Local anesthesia vs general anesthesia
Design
Systematic review and meta-analysis of cohort studies
Follow-up
Perioperative
Authors
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May favor local anesthesia in ruptured EVAR; extends observational meta-analyses but leaves randomized confirmation open.
Meta-Analysis (n=4,336)
Does local anesthesia reduce perioperative mortality compared to general anesthesia in patients undergoing EVAR for ruptured abdominal aortic aneurysm?
Odds Ratio: 0.49 (95% CI 0.35–0.67)
Absolute Event Rate: 17.3% vs 26.4%
p-value: p=<0.00001
Local anesthesia appears to improve perioperative mortality compared to general anesthesia in patients undergoing EVAR for ruptured abdominal aortic aneurysm, particularly in hemodynamically stable patients.
Lei et al. (2022) conducted a meta-analysis in Ruptured abdominal aortic aneurysm (n=4,336). Local anesthesia vs. General anesthesia was evaluated on Perioperative mortality (OR 0.49, 95% CI 0.35-0.67, p=<0.00001). Local anesthesia significantly reduced perioperative mortality compared to general anesthesia during endovascular repair of ruptured abdominal aortic aneurysms (OR 0.49; 95% CI 0.35-0.67; p<0.00001).
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