Key result
Diastolic heart failure (43% of cohort) was strongly correlated with obesity and hypertension, whereas systolic heart failure was associated with diabetes and prior myocardial infarction.
Observational (n=1,426)
Yes
Systolic and diastolic heart failure have distinct clinical and metabolic risk factor profiles, with obesity and hypertension more strongly linked to diastolic HF and diabetes to systolic HF.
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Supports subtype-specific HF prevention research; leaves open causal inference and requires prospective confirmation.
Chinali et al. (2010) conducted an observational in Acute systolic or diastolic heart failure (n=1,426). Diastolic heart failure (EF ≥50%) vs. Systolic heart failure (EF <50%) was evaluated on Prevalence of risk factors and comorbidities. Diastolic heart failure (43% of cohort) was strongly correlated with obesity and hypertension, whereas systolic heart failure was associated with diabetes and prior myocardial infarction.
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