Key result
Cardiac troponin T positivity was significantly more frequent in patients with pulmonary embolism (13.6%) compared to controls with pneumonia or asthma (1.7%), while troponin I positivity did not significantly differ.
Why the study?
Does the measurement of cardiac troponins aid in the diagnosis, prognosis, and differential diagnosis of pulmonary embolism?
Case-Control (n=117)
Yes
Does the measurement of cardiac troponins aid in the diagnosis, prognosis, and differential diagnosis of pulmonary embolism?
This study aims to evaluate the utility of cardiac troponins for diagnosing, prognosticating, and differentiating pulmonary embolism from other hypoxemic pulmonary diseases.
Answers are grounded in this paper and cite their sources.
May support troponin T for differentiating pulmonary embolism; hypothesis-generating and requires prospective validation before clinical use.
Aim: Pulmonary Embolism (PE) is a major cause of deaths in hospitals. Early diagnosis and emergent treatment decrease mortality rate. Cardiac troponins are thought to be useful in early diagnosis and especially in predicting PE prognosis. The aims of this study are 1) to investigate the diagnostic importance of cardiac troponins in PE and 2) to evaluate the relationship between disease severity, right ventricular dilatation and high levels of cardiac troponins. This study also aims to determine the role of cardiac troponins in differential diagnosis of PE from other pulmonary diseases that may also cause hypoxemia.
No takes yet. Share an insight, caveat, or question.
Nalan Demir (2013) conducted a case-control in Pulmonary Embolism (n=117). Cardiac troponin T and I levels vs. Patients with pneumonia and asthma attack was evaluated on Cardiac troponin T (cTnT) positivity (>0.01 ng/ml) (p=0.03). Cardiac troponin T positivity was significantly more frequent in patients with pulmonary embolism (13.6%) compared to controls with pneumonia or asthma (1.7%), while troponin I positivity did not significantly differ.
Synapse has enriched 10 related papers. Consider them for comparative context: