Olanzapine in the treatment of dopaminomimetic psychosis in patients with Parkinson's disease

To the Editor: After reading the article by Wolters et al.1 on the use of olanzapine in dopamimetic psychosis in Parkinson's disease (PD), I began to use it. I have summarized my experience with the use of olanzapine for drug-induced psychosis in akinetic rigid syndromes, including PD. The only patients excluded were those who were prospectively switched from clozapine to olanzapine (submitted for publication). Some patients were started on the drug by other physicians. Some discontinued the drug before an office visit, so before and after evaluations were not always available. As a result, patients were not evaluated in a uniform manner. Information was obtained by telephone if the patient was not seen in the office for follow-up. No attempt was made to keep anti-PD medications unchanged. Any patient who remained on olanzapine was considered a treatment success. Of 19 patients reviewed, 5 women and 14 men were included. Their mean age was …