Key result
Circulating n-3 fatty acid levels were positively associated with flow-mediated dilatation in young smokers (0.045 mm. %(-1); 95% CI 0.011-0.079; P=0.01) and those with higher insulin or glucose.
Why the study?
Are circulating levels of n-3 fatty acids associated with vascular endothelial function in early adulthood?
Population
326 adults (157 males, 169 females, aged 20 to 28 years)
Design
Cross-sectional
Authors
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Supports endothelial benefit of n-3 fatty acids in at-risk youth; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=326)
Are circulating levels of n-3 fatty acids associated with vascular endothelial function in early adulthood?
Effect estimate: 0.045 mm. %(-1) (95% CI 0.011 to 0.079)
p-value: p=0.01
Higher circulating n-3 fatty acid levels are associated with better endothelial function in young adults with cardiovascular risk factors such as smoking, hyperinsulinemia, or hypertriglyceridemia.
C. P. M. Leeson (2002) reported a cross-sectional. Circulating n-3 fatty acid concentrations was evaluated on Flow-mediated brachial artery dilatation (FMD) (0.045 mm. %(-1), 95% CI 0.011 to 0.079, p=0.01). Circulating n-3 fatty acid levels were positively associated with flow-mediated dilatation in young smokers (0.045 mm. %(-1); 95% CI 0.011-0.079; P=0.01) and those with higher insulin or glucose.
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