Key result
Left ventricular aneurysm repair with an endoventricular patch resulted in 15.6% hospital mortality and improved mean ejection fraction from 25.8% to 37.8%.
Why the study?
Does endoventricular patch repair improve functional outcomes and survival in patients with left ventricular aneurysms?
Observational (n=45)
Does endoventricular patch repair improve functional outcomes and survival in patients with left ventricular aneurysms?
Endoventricular patch repair for left ventricular aneurysms significantly improves ejection fraction and functional status with an 86.5% 2-year survival rate.
Answers are grounded in this paper and cite their sources.
May benefit selected patients with left ventricular aneurysms; hypothesis-generating and requires prospective trials before practice change.
BACKGROUND: Recent advances in surgical techniques for the repair of left ventricular aneurysms (LVAs) include the use of an endoventricular patch to exclude the aneurysm cavity. This technique has replaced conventional linear plication of the aneurysm. The endoventricular patch technique remodels the left ventricular cavity to a more physiological geometry that improves function. METHODS AND RESULTS: From December 1989 through November 1993, 45 patients underwent an LVA repair with an endoventricular patch. This procedure was performed in association with coronary artery bypass grafting in 40 patients. Twenty-eight patients (62.2%) also had nonguided encircling subendocardial incisions. Operative procedures included 7 emergency operations, 3 concomitant valve procedures, and a mean of 2.2 bypass grafts per patient. Eight patients had previous cardiac operations. Hospital mortality was 15.6% (7/45) for all patients and 9.1% (3/33) for nonemergent revascularization and LVA repairs. Ejection fraction improved from a mean of 25.8% preoperatively to 37.8% postoperatively; the mean New York Heart Association classification improved from 3.5 to 1.5. Of patients known to have preoperative arrhythmias (inducible or sudden death), 69% were not inducible postoperatively without antiarrhythmic medication. Survival from late cardiac death (including death of unknown origin) was 86.5% at 2 years. Freedom from documented ventricular arrhythmias was 94.3% at 2 years. CONCLUSIONS: These results indicate that the patch endoaneurysmorrhaphy technique can provide an excellent functional and physiological outcome in patients with LVAs and severely impaired ventricular function.
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Grossi et al. (1995) conducted an observational in Left ventricular aneurysm (n=45). Endoventricular patch repair was evaluated on Hospital mortality. Left ventricular aneurysm repair with an endoventricular patch resulted in 15.6% hospital mortality and improved mean ejection fraction from 25.8% to 37.8%.
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