Potential anticonvulsants. V. The condensation of isatins with C‐acetyl heterocyclic compounds

A number of C‐acetyl heterocyclic compounds were condensed with isatin and substituted isatins to give a series of 3‐hydroxy‐3‐substituted oxindoles. The products from 2‐acetylfuran and isatin, 2‐acetylthiophene and isatin, and 2‐acetylpyridine and 1‐methylisatin were active at 100 mg/Kg in the maximal electroshock seizure test.