Key result
Numerical analysis of blood flow in a patient-specific ophthalmic artery revealed hyperemia rather than ischemia, suggesting impaired vision was likely caused by optic nerve compression.
Computational modeling of ophthalmic artery blood flow in an aneurysm patient suggests visual impairment was due to mass effect rather than ischemia.
May suggest mass effect over ischemia in ophthalmic aneurysms; hypothesis-generating for patient-specific flow modeling pending validation.
In this paper we investigate blood flow in the ophthalmic artery (OA) which is the major artery supplying blood to the eyes. An OA and several other cerebral arteries are digitized from a computed tomography angiography (CTA) image of an aneurysm patient. Utilizing a reduced version (1D) of the governing Navier-Stokes equations we solve the transient flow in these arteries. The flow waveform of the patient-OA is compared with that in a healthy vascular tree, and also with published ultrasonic measurements. We found that hyperemia rather than ischemia occurred in the OA, and we suggest that this was unlikely to be the cause of impaired vision in the patient. A more likely explanation is the compression of the optic nerves caused by the mass of the aneurysm.
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Ho et al. (2011) studied Aneurysm with impaired vision (n=1). Numerical analysis of blood flow (1D Navier-Stokes) vs. Healthy vascular tree and published ultrasonic measurements was evaluated on Blood flow waveform (hyperemia vs ischemia). Numerical analysis of blood flow in a patient-specific ophthalmic artery revealed hyperemia rather than ischemia, suggesting impaired vision was likely caused by optic nerve compression.
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