Key result
Overexpression of HSDL2 was associated with cervical cancer progression, including lymph node metastasis and recurrence, and promoted tumorigenesis by regulating lipid metabolism.
Why the study?
The role of HSDL2 in cervical cancer and whether it regulates cervical cancer progression through lipid metabolism was unclear.
Population
Cervical cancer cells (Hela, C33A, and SiHa)
Authors
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HSDL2 may aid risk stratification in cervical cancer; leaves open validation as therapeutic target.
HSDL2 promotes cervical cancer cell proliferation and metastasis via lipid metabolism and EMT, highlighting its potential as a prognostic biomarker and therapeutic target.
Yang et al. (2021) studied Cervical cancer. HSDL2 overexpression was evaluated on Cervical cancer progression (lymph node metastasis, recurrence, proliferation, invasion, migration). Overexpression of HSDL2 was associated with cervical cancer progression, including lymph node metastasis and recurrence, and promoted tumorigenesis by regulating lipid metabolism.
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