Key result
Xanthine oxidase inhibitors, particularly allopurinol, have proven efficacy as second-line drugs in patients with chronic stable ischaemic heart disease, though their role in other manifestations remains controversial.
Why the study?
Do xanthine oxidase inhibitors like allopurinol improve clinical outcomes and symptoms in patients with ischaemic heart disease?
Population
Patients with ischaemic heart disease, including chronic stable angina pectoris, patients referred for…
Design
Review
Authors
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May improve exercise tolerance in stable angina; hypothesis-generating for xanthine oxidase inhibitors in ischaemic heart disease.
Do xanthine oxidase inhibitors like allopurinol improve clinical outcomes and symptoms in patients with ischaemic heart disease?
Allopurinol demonstrates beneficial anti-ischaemic effects in chronic stable angina and patients undergoing angioplasty, supporting its potential role in managing ischaemic heart disease.
Zdrenghea et al. (2017) conducted a review in Ischaemic heart disease. Xanthine oxidase inhibitors was evaluated. Xanthine oxidase inhibitors, particularly allopurinol, have proven efficacy as second-line drugs in patients with chronic stable ischaemic heart disease, though their role in other manifestations remains controversial.
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