Key result
Biaxial mechanical testing of murine right ventricular free wall specimens revealed distinct mechanical anisotropy, with the apex-to-outflow-tract direction being the stiffer axis.
Population
7 murine right ventricular free wall (RVFW) specimens
Design
Preclinical
Authors
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Provides murine RV biomechanical baseline; leaves open disease remodeling mechanisms and clinical translation.
This study establishes a murine model and analysis method linking right ventricular tissue microstructure to its biomechanical behavior, providing a foundation for understanding RV remodeling in disease.
Valdez‐Jasso et al. (2012) studied Right-ventricular biomechanics (n=7). Biaxial mechanical testing was evaluated on Mechanical anisotropy and fiber orientation. Biaxial mechanical testing of murine right ventricular free wall specimens revealed distinct mechanical anisotropy, with the apex-to-outflow-tract direction being the stiffer axis.