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Introduction Worldwide, it has been reported that fully vaccinated people still died of COVID-19-associated symptoms, generating public uncertainty about the safety and effectiveness of the vaccines. Hence, this research is aimed at assessing the incidence of COVID-19 breakthrough infection among vaccinated Health Workers and the possible effect of changes in the practice of post-vaccination safety precautions. Method This was a Health facility-based descriptive cross-sectional study. Data were collected using self-administered questionnaires distributed at the participant’s work unit across the selected health facilities. The nasopharyngeal specimen was also obtained from the participants and analysed using STANDARD Q COVID-19 Ag Test rapid chromatographic immunoassay for the detection of antigens to SARS-CoV-2. All data were input and analyzed using SPSS version 20. Results There was a statistically significant relationship between the vaccination status of respondents and the post-vaccination test result (χ2 = 6.816, df =1, p= 0.009). The incidence of covid-19 infection among the vaccinated and unvaccinated HCWs was 2 % and 8 % respectively. 5 of the 15 respondents who tested positive for covid-19 had been fully vaccinated. However, all 5 of them did not practice safety measures after vaccination. None of the respondents who practised safety measures after vaccination tested positive for covid-19. The remaining 10 respondents that tested positive for covid-19 had not been vaccinated though they practised safety precautions. Conclusion Vaccination and the practice of safety precautions will go a long way to preventing future Covid-19 breakthrough infections.
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Osho et al. (2023) studied this question.