Key result
In a case series of four pregnancies complicated by TRAP sequence, clinical manifestations and outcomes varied widely, highlighting the need for early detection and individualized management.
Case Report (n=4)
Yes
TRAP sequence presents with significant heterogeneity in clinical manifestations and course, requiring individualized expectant or interventional management.
May inform counseling in rare TRAP cases; leaves open optimal interventions pending prospective data.
Twin reversed arterial perfusion (TRAP) sequence is a rare but severe condition that affects monochorionic (MC) multifetal pregnancies. In twin pregnancies, it is characterized by a normally developed twin and another twin with missing heart function (acardiac twin or TRAP twin). A variety of risks and complications may affect the normal twin. Management of such pregnancies can be either expectant or interventional. We report four cases of TRAP sequence treated in our institutions and supply an overview on currently existing literature. This case series demonstrates the heterogeneity in manifestations and clinical course of patients affected by this condition. Furthermore, it includes an acardius amorphous of considerable size delivered at 35.6 weeks of gestation.
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Quaas et al. (2021) conducted a case report in Twin reversed arterial perfusion (TRAP) sequence (n=4). Management of TRAP sequence (expectant or fetoscopic laser surgery) was evaluated on Clinical course and fetal outcomes. In a case series of four pregnancies complicated by TRAP sequence, clinical manifestations and outcomes varied widely, highlighting the need for early detection and individualized management.
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