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November 5, 2022Chinese Medical JournalOpen Access

Pregnant women with GDM had higher average glucose levels during the intrapartum and early postpartum periods compared to non-diabetic pregnancies (95.5 vs. 89.1 mg/dL, P=0.008).

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Why the study?

Data on the glycemic profile of pregnant women with gestational diabetes mellitus during the perinatal period were sparse.

Do pregnant women with gestational diabetes mellitus have different intrapartum and early postpartum glucose profiles compared to women with non-diabetic pregnancies?

Population

124 pregnant women admitted for childbirth

Comparison

GDM receiving lifestyle interventions alone vs matched non-diabetic pregnancies

Design

Prospective observational study

Follow-up

Within 24 h after placental delivery

Key result

Pregnant women with GDM had higher average glucose levels during the intrapartum and early postpartum periods compared to non-diabetic pregnancies (95.5 vs. 89.1 mg/dL, P=0.008).

Authors

YDYu DingXZXueying ZhengYLYujie Liu

Discussion

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Overview

Offers perinatal glucose profiles in GDM; leaves open links to outcomes or practice changes.

Study Design

Type

Observational (n=124)

Structured PICO

Do pregnant women with gestational diabetes mellitus have different intrapartum and early postpartum glucose profiles compared to women with non-diabetic pregnancies?

P
Population
124 pregnant women (mean age 29.5 years), including 60 with GDM on lifestyle interventions and 64 matched non-diabetic pregnancies, monitored during intrapartum and early postpartum periods.
E
Exposure
Gestational diabetes mellitus (GDM) receiving lifestyle interventions alone
C
Comparator
Matched women with non-diabetic pregnancies (NDPs)
O
Outcome
Intrapartum and early postpartum glucose profiles measured via flash glucose monitoring (FGM)surrogate

Main Result

Absolute Event Rate: 95.5% vs 89.1%

p-value: p=0.008

Pregnant women with GDM managed with lifestyle interventions alone exhibit higher early postpartum glucose levels and variability compared to normoglycemic women, suggesting a need for modified postpartum monitoring.

Cite This Study

Ding et al. (2022) conducted an observational in Gestational diabetes mellitus (n=124). Gestational diabetes mellitus vs. Non-diabetic pregnancies was evaluated on Average glucose level during the intrapartum and early postpartum periods (p=0.008). Pregnant women with GDM had higher average glucose levels during the intrapartum and early postpartum periods compared to non-diabetic pregnancies (95.5 vs. 89.1 mg/dL, P=0.008).

synapsesocial.com/papers/6a9e4dfd37bba822732cb525https://doi.org/10.1097/cm9.0000000000002423
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Glycemic changes during first 48 h postpartum in mothers with gestational diabetes mellitus and non—diabetic mothers – a comparative study2026
  2. 2Analysis of glucose metabolism outcomes 4–7 years postpartum in women with gestational diabetes mellitus using continuous glucose monitoring maternal risk factors: a Chinese cohort study2025 · 1 citations
  3. 3The metabolic and circadian signatures of gestational diabetes in the postpartum period characterised using multiple wearable devices2024 · 8 citations
  4. 4PREVALENCE OF GLUCOSE INTOLERANCE IN POST-PARTUM WOMEN WITH HISTORY OF GESTATIONAL DM2024
  5. 5Examination of gestational diabetes mellitus at a tertiary care hospital2024 · 1 citations