Key result
A 49-year-old woman developed a rare low-grade myofibroblastic sarcoma in the retropectoral area 16 years after receiving adjuvant radiotherapy for invasive ductal carcinoma.
Why the study?
Radiation-induced low-grade myofibroblastic sarcoma following breast cancer radiotherapy is extremely rare, with only one previous mammary case reported and prior studies primarily focusing on pathological rather than clinical and radiological findings.
Case Report (n=1)
No
This case report highlights the clinical and radiological features of a rare radiation-induced low-grade myofibroblastic sarcoma occurring 16 years after breast-conserving surgery and radiotherapy.
Supports vigilance for rare late RT-induced sarcomas in breast survivors; leaves open incidence and surveillance needs.
Low-grade myofibroblastic sarcoma (LGMFS) is a rare type of sarcoma, and its manifestation as a radiotherapy (RT)-induced sarcoma following RT for breast cancer is even more unusual. To date, only one case of RT-induced mammary myofibroblastic sarcoma (MFS) has been reported. Here we present the case of a 49-year-old woman with LGMFS after undergoing breast-conserving surgery for invasive ductal carcinoma (IDC), and with a history of RT 16 years prior. Due to the rarity of this disease, previous studies have focused primarily on the pathological findings of MFS. In this report however, we present the clinical and radiological features of LGMFS in the retro pectoral area as a rare type of RT-induced sarcoma.
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Park et al. (2023) conducted a case report in Low-grade myofibroblastic sarcoma (n=1). Adjuvant radiotherapy was evaluated on Diagnosis of low-grade myofibroblastic sarcoma. A 49-year-old woman developed a rare low-grade myofibroblastic sarcoma in the retropectoral area 16 years after receiving adjuvant radiotherapy for invasive ductal carcinoma.
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