Key result
Abundance of muscle spindles and their intrafusal-fibre composition are substantially determined by genetic factors, with mean spindles per muscle ranging from 9 to 13 across strains (P<0.02).
Authors
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Strain-specific spindle variation requires genetic controls in animal models; leaves open translation to human cardiovascular proprioception.
p-value: p=< 0.02
Lionikas et al. (2013) studied Healthy (inbred mouse strains). Inbred mouse strains vs. Between-strain comparison was evaluated on Number of muscle spindles per muscle (p=< 0.02). Abundance of muscle spindles and their intrafusal-fibre composition are substantially determined by genetic factors, with mean spindles per muscle ranging from 9 to 13 across strains (P<0.02).
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