Key result
Cardiac hypertrophy commonly occurs with disturbances that increase the work of the heart, though in some conditions like myocarditis, the cause of hypertrophy is less clear.
Supports workload assessment in hypertrophy evaluation; leaves open mechanisms in myocarditis for targeted research.
CARDIAC hypertrophy commonly occurs with disturbances that increase the work of the heart. These include valvular defects, intracardiac or other vascular shunts and hypertension of either the pulmonary or the systematic circuits. In these situations the cause is apparent and the result follows naturally. The heart is subjected to unusual or excessive work, and it follows that the myocardium enlarges in a manner analogous to the development of increased muscle mass in weight lifters and wrestlers.Other conditions with myocardial hypertrophy exist, however, in which the cause is either less clear or totally obscure. Myocarditis may result in myocardial hypertrophy, . . .
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Connolly et al. (1951) conducted a review in Cardiac hypertrophy. Cardiac hypertrophy commonly occurs with disturbances that increase the work of the heart, though in some conditions like myocarditis, the cause of hypertrophy is less clear.
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