Characterization of the Silver Nanoparticles in the Sovereign Silver® and Argentyn 23®, Bio-Active Silver Hydrosol™ Products [Letter]

Sovereign Silver and Argentyn 23 are the brand names of the Bio-Active Silver Hydrosol manufactured by Natural Immunogenics Corp (NIC). The products contain a mixture of positively charged silver ions and silver nanoparticles. In a 2020 publication by Kumar et al., 1 Sovereign Silver and Argentyn 23 were included as part of a "comparative evaluation of commercial colloidal silver products". This publication concluded that there were no silver nanoparticles (AgNPs) present neither in the Sovereign Silver nor the Argentyn 23 products. This letter aims at providing a perspective omitted in the aforementioned publication and supporting the manufacturer's marketing message as it relates to the presence of silver nanoparticles in its products, by providing detailed characterization using TEM and AFM.